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Autoimmune hepatitis

Autoimmune hepatitis (AIH) is a rare condition and caused by the body’s immune system attacking the liver. It can affect all age groups, all ethnic groups and all geographical regions though there is a predominance in females.

Autoimmune hepatitis was previously called lupoid hepatitis, as most patients had systemic lupus erythematosus, and also chronic active hepatitis (CAH).

SYMPTOMS OF AUTOIMMUNE HEPATITIS

Initial symptoms may include fatigue, muscle aches, fever, abdomen pain and jaunice (yellowing of skin and the whites of the eyes). Other symptoms may include weight loss and pain in the small joints of fingers. It is often seen in people with other autoimmune conditions such as rheumatoid arthritis, celiac disease or autoimmune thyroiditis (Hashimto's), primary biliary cirrhosis and primary sclerosing cholangitis.
liver diagram



LATEST RESEARCH ON AUTOIMMUNE HEPATITIS
13th July 2017: Association of autoimmune hepatitis with Src homology 2 adaptor protein 3 gene polymorphisms in Japanese patients
Takeji Umemura, Satoru Joshita, Hideaki Hamano, Kaname Yoshizawa, Shigeyuki Kawa, Eiji Tanaka and Masao Ota

Abstract
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease characterized by an autoimmune reaction to hepatocytes. Read more

May 2017: Autoimmune hepatitis: review of histologic features included in the simplified criteria proposed by the international autoimmune hepatitis group and proposal for new histologic criteria
Dana Balitzer, Nafis Shafizadeh, Marion G Peters, Linda D Ferrell, Najeeb Alshak and Sanjay Kakar

Abstract
Simplified criteria for diagnosis of autoimmune hepatitis are based on autoantibodies, serum immunoglobulin G, histologic features, and negative viral serology. Read more

22nd April 2017: Immunoserological and histological differences between autoimmune hepatitis with acute presentation and chronic autoimmune hepatitis

Authors
Kazufumi Dohmen, Hirofumi Tanaka, Masatora Haruno, Shinichi Aishima
The histological features of clinically chronic autoimmune hepatitis (AIH) have been well established, with interface hepatitis and plasma cell infiltration as hallmark lesions, however, the immunoserological and histological features of recent-onset and acute AIH remain undefined. Read on

2017: Recurrent Autoimmune Liver Diseases After Liver Transplantation
A. J. Montano-Loza; R. A. Bhanji; S. Wasilenko; A. L. Mason

Indications for liver transplantation (LT) in patients with autoimmune hepatitis (AIH) Read more at Medscape
31st August 2016: Autoimmune hepatitis: current challenges and future prospects
Aizawa Y, Hokari A

Autoimmune hepatitis (AIH) is a chronic progressive liver disease characterized by high levels of aminotransferases and autoantibodies, hypergammaglobulinemia, and interface hepatitis. Read more


Liver diagram

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